赌博app

性别:男
职称: 副教授
学历:博士研究生
电子邮件: [email protected]
导师类型: 博士生导师
学科方向:070703-海洋生物学
0860-生物与医药

研究方向

【办公室：生命科学楼2号413】

1.水产动物免疫学与病原学的基础研究

2.水产动物疫病流行病学及防控技术体系构建

3.鱼类新型疫苗和抗病制剂创制

个人经历

2006年获赌博app-网络赌博软件 水生生物学博士学位，同年留校工作。

2009-2010年新加坡国立大学淡马锡生命科学研究所公派访问学者。

2017年至今任赌博app-网络赌博软件 副教授。

讲授课程

本科课程：《遗传学实验》（必修）、《生产实习（水生生物学）》（专选）、《大学生物》（遗传学部分）（必修）、《遗传学讨论课》（选修）。

研究生课程：《高级海洋生物学》、《病虫害检测与生物控制》。

学术成就

谢俊锋，副教授，博士生导师，研究方向为海洋动物免疫与病原分子生物学，水产动物疫病防控与健康养殖全国重点实验室主任助理。主要从事水生动物病害防控技术、相关疫苗和抗病分子的开发研制及病毒和宿主功能基因研究。首次将RNAi技术运用于水产病毒防控并开发了虎纹蛙虹彩病毒（TFV）防控技术。建立了神经坏死病毒（NNV）综合防控体系，包括病毒类似物疫苗和病毒表面展示疫苗等新型安全疫苗、单链抗体和小分子多肽等抗病毒制剂，疫苗和抗病毒制剂的配合运用能有效防治病毒的爆发，减少养殖鱼类仔稚鱼的死亡及经济损失。同时开展流行病学、病毒结构、细胞运输、细胞信号传导、病毒和宿主互作等病毒学基础研究。

承担课题

2023-2026 国家自然科学基金面上项目，主持

2020-2023 国家自然科学基金面上项目，主持

2023-2025 广东省自然科学基金面上项目，主持

2021-2023 广东省自然科学基金面上项目，主持

2022-2025 中国—东盟海水养殖技术“一带一路”联合实验室建设与海水养殖技术联合研究，骨干

2019-2021 广东省科技计划项目重点领域研发计划，骨干

2015-2018 广东省科技计划农村科技领域重点项目，主持（已结题）

2014-2018 国家自然科学基金重点项目，骨干（已结题）

论文专著

Siyou Huang^#, Yujia Wu^#, Lianpan Su, Taowen Su, Qiong Zhou, Jing Zhang, Zhiying Zhao^*, Shaoping Weng, Jianguo He, Junfeng Xie^*. A single-chain variable fragment antibody exerts anti-nervous necrosis virus activity by irreversible binding. Aquaculture. 2022;522: 738001.

Qiong Zhou, Jing Zhang, Runqing Huang, Siyou Huang, Yujia, Wu, Lijie, Huang, Jianguo He, Junfeng Xie^*. An affinity peptide exerts antiviral activity by strongly binding nervous necrosis virus to block viral entry. Fish and Shellfish Immunology. 2019;86:465-73.

Runqing Huang, Qiong Zhou, Yan Shi, Jing Zhang, Jianguo He, Junfeng Xie^*. Protein A from orange-spotted grouper nervous necrosis virus triggers type I interferon production in fish cell. Fish and Shellfish Immunology. 2018;79:234-243.

Runqing Huang, Guohua Zhu, Jing Zhang, Yuxiong Lai, Yu Xu, Jianguo He, Junfeng Xie^*. Betanodavirus-like particles enter host cells via clathrin-mediated endocytosis in a cholesterol-, pH- and cytoskeleton-dependent manner. Veterinary Research. 2017;48: 8.

Runqing Huang, Jing Zhang, Guohua Zhu, Jianguo He, Junfeng Xie^*. The core ubiquitin system of mandarin fish, Siniperca chuatsi, can be utilized by infectious spleen and kidney necrosis virus. Fish and Shellfish Immunology. 2017;70:293-301.

Junfeng Xie^#, Kunpeng Li^#, Yuanzhu Gao^#, Runqing Huang, Yuxiong Lai, Yan Shi, Shaowei Yang, Guohua Zhu, Qinfen Zhang^*, Jianguo He^*. Structural analysis and insertion study reveal the ideal sites for surface displaying foreign peptides on a betanodavirus-like particle. Veterinary Research. 2016;47:16.

Junfeng Xie^*, Runqing Huang, Yuxiong Lai. Chapter 15: Prokaryotic Production of Virus-Like Particle Vaccine of Betanodavirus. Methods in Molecular Biology, Vaccine Design 2016;1404:211-23.

Yuxiong Lai, Baolei Jin, Yu Xu, Lijie Huang, Runqing Huang, Yong Zhang, Jimmy Kwang*, Jianguo He, Junfeng Xie^*. Immune responses of orange-spotted grouper, Epinephelus coioides, against virus-like particles of betanodavirus produced in Escherichia coli. Veterinary Immunology and Immunopathology 2014;157(1-2):87-96.

Junfeng Xie, Yuxiong Lai, Lijie Huang, Runqing Huang, Shaowei Yang, Yan Shi, Shaoping Weng, Yong Zhang, Jianguo He^*. Genome-wide analyses of proliferation-important genes of Iridovirus-tiger frog virus by RNAi. Virus Research. 2014;189:214-225.

Wen Huang^#, Qizhi Liu^#, Junfeng Xie, Weimin Wang, Jun Xiao, Shuisheng Li, Haifa Zhang, Yong Zhang^*, Shaojun Liu^*, Haoran Lin. (2014), Characterization of triploid hybrid groupers from interspecies hybridization (Epinephelus coioides ♀ × Epinephelus lanceolatus ♂). Aquaculture Research. 2014;47(7): 2195-2204.

Bailiang He, Jimin Yuan, Luyun Yang, Junfeng Xie, Shaoping Weng, Xiaoqiang Yu, Jianguo He^*. The Viral TRAF Protein (ORF111L) from Infectious Spleen and Kidney Necrosis Virus Interacts with TRADD and Induces Caspase 8-mediated Apoptosis. PLoS ONE. 2012;7(5):e37001.

Yihong Chen^#, Xiaoting Jia^#, Xiande Huang, Shuang Zhang, Mei Li, Junfeng Xie, Shaoping Weng, Jianguo He^*. Two Litopenaeus vannamei HMGB proteins interact with transcription factors LvSTAT and LvDorsal to activate the promoter of white spot syndrome virus immediate-early gene ie1，Molecular Immunology. 2011;48(5):793–799.

Qing Wang^#, Yongwen Luo^#, Junfeng Xie, Chuanfu Dong, Shaoping Weng, Huashui Ai, Ling Lv, Xiuqun Yang, Xiaoqiang Yu, Jianguo He^*. Identification of two novel membrane proteins from the Tiger frog virus (TFV). Virus Research. 2008;136:35-42.

Junfeng Xie^#, Jingyi Zhu^#, Hongyan Yang, Shaoping Weng, Cheng Chen, Hao Chen, Qi Xie, Mengfeng Li, Jianguo He^*. RING finger proteins of infectious spleen and kidney necrosis virus (ISKNV) function as ubiquitin ligase enzymes. Virus Research. 2007;123:170-177.

Junfeng Xie^#, Ling Lv^#, Min Deng^#, Shaoping Weng, Jingyi Zhu, Yue Wu, Lin Gan, Siu-Ming Chan, Jianguo He^*. Inhibition of reporter gene and Iridovirus-tiger frog virus in fish cell by RNA interference. Virology. 2005;338:43-52.